Calculate eGFR by CKD-EPI 2021 (untested) — leo_eGFR

Usage

leo_eGFR_v2021(
  gender,
  age,
  creatinine,
  creatinine_unit = c("umol/L", "mg/dL"),
  ...
)

Arguments

gender: Numeric/character vector for sex, usually from UKB field p31 (0 = Female, 1 = Male).
age: Numeric/character vector for age in years, usually from UKB field p21003.
creatinine: Numeric/character vector for serum creatinine, usually from UKB field p30700.
creatinine_unit: Unit of creatinine, either "umol/L" (UKB default) or "mg/dL".
...: Reserved for future use.

Value

Numeric vector of eGFR values (mL/min/1.73m^2).

Details

Estimate glomerular filtration rate (eGFR, mL/min/1.73m^2) using the 2021 CKD-EPI creatinine equation. This is the race-free creatinine-only equation currently highlighted by NIDDK for adult eGFR reporting.

Note

UK Biobank-friendly inputs are p31, p21003_i0, and p30700_i0. When creatinine_unit = "umol/L" (default), creatinine is converted internally to mg/dL by dividing by 88.4. Use age and creatinine from the same assessment instance when possible. This function is currently untested on real UKB export files.

References

https://www.niddk.nih.gov/research-funding/research-programs/kidney-clinical-research-epidemiology/laboratory/glomerular-filtration-rate-equations/adults https://biobank.ndph.ox.ac.uk/ukb/field.cgi?id=31 https://biobank.ndph.ox.ac.uk/ukb/field.cgi?id=21003 https://biobank.ndph.ox.ac.uk/ukb/field.cgi?id=30700

Examples

leo_eGFR_v2021(gender = c(1, 0), age = c(45, 62), creatinine = c(78.5, 92.3))
#> ℹ Calculating eGFR using CKD-EPI 2021 (umol/L -> mg/dL if needed)
#> ✔ [10:00:39] eGFR v2021 finished for 2 records
#> [1] 107.7711  60.4818