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Batch Adjust SMR Results with FDR and Bonferroni Corrections

leo_smr_adjust_loop.Rd

This function applies FDR/Bonferroni corrections to all SMR results within a specified directory.

Usage

leo_smr_adjust_loop(
  dir,
  out_dir = "",
  pattern = "\\.smr$",
  QTL_type,
  Source,
  ...
)

Arguments

dir

Character. The directory containing SMR result files. Files should have the .smr extension and follow the naming convention exposure@outcome.smr.

out_dir

Character. The output directory where the adjusted SMR files will be saved. If not specified, defaults to creating a fdr directory within the input directory.

pattern

Character. A regular expression pattern to match SMR result files. Default is "\.smr$" (i.e., files ending with .smr).

QTL_type

Character. Type of QTL (e.g., "eQTL", "sQTL").

Source

Character. Source of the data (e.g., "GTEx", "Westra").

...

Additional arguments to be passed to leo_smr_adjust.

Value

NULL.

Examples

if (FALSE) { # \dontrun{
leo_smr_adjust_loop(dir     = "./output/smr/sqtl/GTEx49/chr_combined",
                    out_dir = "./output/smr/sqtl/GTEx49/fdr")
} # }