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Combine SMR Results for All Chromosomes

combine_smr_res_chr.Rd

This function combines SMR (Summary-data-based Mendelian Randomization) result files across all chromosomes for each unique exposure and outcome pair (Yes, we can deal with multiple exposure in one dir (for say, the 49 sqtl from GTEx)). The combined results are saved to a specified output directory.

Usage

combine_smr_res_chr(dir, out_dir = "")

Arguments

dir

Character. The directory containing SMR result files. Files should follow the naming convention exposure_chrX@outcome.smr, where X represents the chromosome number.

out_dir

Character. The output directory where combined SMR files will be saved. If not specified, defaults to a subdirectory named chr_combined within dir.

Examples

if (FALSE) { # \dontrun{
# Combine SMR results in the "data/smr_results" directory and save to default output directory
combine_smr_res_chr(dir = "data/smr_results")

# Combine SMR results and specify a custom output directory
combine_smr_res_chr(dir = "data/smr_results", out_dir = "data/combined_results")
} # }